<h5>A Big Discovery</h5><p>Scientists from Google DeepMind and Yale University have built a smart computer program that may help doctors fight cancer in the future.</p><p>This new AI model found a new way to help the body’s immune system see and attack cancer cells. When scientists tested the idea in the lab, it worked just like the AI said it would!</p><h5>How the AI Understands Cells</h5><p>The AI is called Cell2Sentence-Scale 27B, or C2S-Scale for short. It was made using Google’s Gemma-2 system, which helps computers learn and understand big and complicated information.</p><p>Our body has trillions of tiny cells. Each cell has genes, like small instruction books that tell it what to do. When a gene is active, it makes RNA, which gives orders to the cell, just like a worker following a plan.</p><p>Scientists used a special method called single-cell RNA sequencing to see what was happening inside each cell. It’s like taking a close-up photo of what a single cell is doing.</p><p>The AI studied data from over 50 million human cells and turned this into short “cell sentences.” By reading millions of these, it learned how different cells behave and communicate with each other.</p><h5>How Cancer Cells Hide</h5><p>Healthy cells show tiny “ID cards” on their surface called antigens. These help the immune system check if the cells are normal.</p><p>But cancer cells can hide by showing fewer ID cards. They do this by lowering something called MHC-I, which helps display those cards.</p><p>The AI made a smart guess: a drug called silmitasertib could make cancer cells show their ID cards, but only if used with a small amount of interferon. Interferon is a natural signal in our body that warns cells when something is wrong and helps the immune system fight back.</p><h5>The AI’s Idea Worked!</h5><p>Scientists at Yale University tested this in the lab.</p><p>When they used silmitasertib alone, nothing big happened. When they used interferon alone, there was only a small change. But when both were used together, the cancer cells showed about 50% more antigens on their surface.</p><p>This meant the immune system could now find and attack the cancer cells, exactly as the AI predicted!</p><h5>A New Hope</h5><p>This discovery shows that AI can do more than just study information; it can help scientists find new ideas to treat diseases. This could help make some hidden (“cold”) tumors easier to find and treat (“hot”).</p><p>It’s still early, but this gives hope that one day, humans and AI can work together to defeat dangerous diseases.</p>

Google DeepMind and Yale University’s new AI model, C2S-Scale, has discovered a way to make cancer cells visible to the immune system, offering hope for better cancer treatments in the future.

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